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While proteins typically can contain hundreds or thousands of amino acids folded into complex structures, peptides are much shorter and simpler

- Cells were allowed to grow beyond confluency: Passage mammalian cells when they are in the log-phase before they reach confluency

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For instance, the yak bone collagen hydrolysates withstand gastrointestinal digestion and significantly alter gut microbiota composition, reducing the Firmicutes to Bacteroidetes ratio by 30.8% and 36.5%, respectively, while increasing short-chain fatty acid concentrations by 50%, demonstrating their potential in functional food applications [117]